Morton's neuroma (growth of a nerve tissue) is a mild and nonprogressive growth of a nerve tissue (intermetatarsal plantar nerve), most commonly of the third and fourth toes (intermetatarsal spaces).

Morton's neuroma is characterised by numbness and pain, relieved by removing footwear.

Morton's neuroma Symptoms include: pain on weight bearing, frequently after only a short time; the pain is felt as a shooting pain affecting the contiguous halves of two toes. Burning, numbness and parasthesia may also be experienced.

The pain is caused by pressure on the enlarged section of nerve where it passes between the metatarsal heads, and is squeezed between them.

The first toe is usually not involved. Neuroma in the 4th/5th interdigital space is described, but is extremely rare.

Morton's neuroma lesions have been found using MRI in patients without symptoms.

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